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新浦京8883平台
师资力量

李晓伟     特聘研究员,博士生导师

研究方向:有机超分子功能材料;生物纳米技术

联系方式:028-85418755          Email:lixw@scu.edu.cn

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简历:

学习及工作经历

2021.12-至今 新浦京8883平台,特聘研究员

2017.09-2020.11 美国爱荷华州立大学,化学系,博士后,导师:Yan Zhao 教授

2012.09-2017.06 四川大学,化学学院,硕博连读,博士,导师:袁立华 教授

2008.09-2012.06 四川大学,化学学院,本科,导师:袁立华 教授

学术兼职

Chinese Chemical Letters(中国化学快报)第四届青年编委会委员

主要研究方向

1)新型超分子主体(分子笼、机械互锁分子、拓扑编织结构)的设计合成,及其在仿生识别、模拟酶催化以及有机物吸附分离方面的应用

2)柔性多孔聚合物、框架材料的设计合成与功能应用

课题组成立于202112月,欢迎对有机化学、超分子化学以及化学生物学等交叉学科研究感兴趣的本科生、研究生加入。此外有攻读博士学位意向的优秀同学可直接与课题组长联系。

长期诚招博士后、研究助理、博士、硕士研究生以及联合培养学生。欢迎对科研具有浓厚兴趣的本科生进组开展“大创”项目和本科毕业论文设计。

主要工作业绩

设计构建具有仿生识别功能的有机功能分子和仿生纳米材料在环境科学、功能材料、生物医药及生命健康等领域具有重要的应用潜力。李晓伟博士致力于有机超分子化学、先进功能材料与纳米生物技术等交叉学科领域的研究,2021年入选四川大学校双百人才工程B计划,主持国家自然科学基金青年项目、四川大学引进人才项目。截至目前,以第一作者或通讯作者在J. Am. Chem. Soc.Angew. Chem. Int. Ed.Chem. Sci. ACS Catal. J. Catal.Chem. Commun.等学术期刊发表发表学术论文10余篇,其中包括多篇封面文章、扉页文章,相关研究工作被X-molChem Views Wiley Chem等学术科技媒体作亮点报道。

主要奖励和荣誉

2021 四川大学双百B人才项目;

2017 四川大学优秀博士毕业生;

2015 博士研究生国家奖学金;

2012 四川大学本科优秀毕业论文一等奖

代表性成果(获奖成果、专著、论文、专利)

1. Xiaowei Li, Yan Zhao* Environmental Modulation of Chiral Prolinamide Catalysts for Stereodivergent Conjugate Addition. J. Catal. 2022, 406, 126-133.

2. Yidan Zhou,‡ Jinyang Wu,‡ Zejiang Liu, Weitao Xu, Menglong Liu, Along Jia, Yuchen Liu, Xiao Xin, Xiaowei Li,* Lihua Yuan* Threading of Three Rings on Two Stations: a Convergent Approach to [4]Rotaxane. Chem. Commun. 2021, 13506-13509. (Cover)

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3. Xiaowei Li, Milad Zangiabadi, Yan Zhao* Molecularly Imprinted Synthetic Glucosidase for the Hydrolysis of Cellulose in Aqueous and Nonaqueous Solutions. J. Am. Chem. Soc. 2021, 143, 5172-5181.

4. Xiaowei Li, Kaiqian Chen, Yan Zhao* Sequence-Selective Protection of Peptides from Proteolysis. Angew. Chem., Int. Ed. 2021, 60, 11092-11097. (Frontispiece, Hot paper )

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5. Xiaowei Li, Tania M. Palhano Zanela, Eric S. Underbakke, Yan Zhao* Controlling Kinase Activities by Selective Inhibition of Peptide Substrates. J. Am. Chem. Soc. 2021, 143, 639-643.

6. Xiaowei Li, Yan Zhao* Synthetic Glycosidase for Precise Hydrolysis of Oligosaccharides and Polysaccharides. Chem. Sci. 2021, 12, 374-383.

7. Xiaowei Li, Yan Zhao* Synthetic Glycosidase Distinguishing Glycan and Glycosidic Linkage in Its Catalytic Hydrolysis. ACS Catal. 2020, 10, 13800-13808.

8. Xiaowei Li, Yan Zhao* Chiral Gating for Size- and Shape-Selective Asymmetric Catalysis. J. Am. Chem. Soc. 2019, 141, 13749-13752. (Selected as supplementary cover, highlighted in Chemistry Views, X-mol).

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9. Xiaowei Li, Xiangyang Yuan, Pengchi Deng, Lixi Chen, Yi Ren, Chengyuan Wang, Lixin Wu, Wen Feng, Bing Gong and Lihua Yuan* Macrocyclic Shape-Persistency of Cyclo[6]aramide Results in Enhanced Multipoint Recognition for Highly Efficient Template-Directed Synthesis of Rotaxanes. Chem. Sci. 2017, 8, 2091-2100.

10. Xiaowei Li, Bao Li, Long Chen, Jinchuan Hu, Chengdanyang Wen, Qingdong Zheng, Lixin Wu, Huaqiang Zeng, Bing Gong* and Lihua Yuan* Liquid-Crystalline Mesogens Based on Cyclo[6]aramides: Distinctive Phase Transitions in Response to Macrocyclic Host-Guest Interactions. Angew. Chem., Int. Ed. 2015, 54, 11147-11152.

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11. Shanshan Shi, Yumin Zhu, Xiaowei Li, Xiangyang Yuan, Teng Ma, Wen-Li Yuan, Guo-Hong Tao, Wen Feng and Lihua Yuan* Ion-Pair Recognition of Amidinium Salts by Partially Hydrogen-Bonded Heteroditopic Cyclo[6]aramide. RSC Adv. 2016, 6, 39839-39845.

12. Long Chen, Zhiyong Peng, Shuo Liu, Xiaowei Li, Rongzhou Chen, Yi Ren, Wen Feng and Lihua Yuan* “Cyclo[6]aramide-Tropylium Charge Transfer Complex as a Colorimetric Chemosensor for Differentiation of Intimate and Loose Ion Pairs” Org. Lett. 2015, 17, 5950-5953.

13. Youzhou He, Min Xu, Rongzhao Gao, Xiaowei Li, Fengxue Li, Xuedan Wu, Dingguo Xu*, Huaqiang Zeng and Lihua Yuan* “Two-Component Supramolecular Gels Derived from Amphiphilic Shape-Persistent Cyclo[6]aramides for Specific Recognition of Native Arginine” Angew. Chem., Int. Ed. 2014, 53, 11834-11839.

14. Jinchuan Hu, Long Chen, Yi Ren, Pengchi Deng, Xiaowei Li, Youjia Wang, Yiming Jia, Jian Luo, Xinshi Yang, Wen Feng* and Lihua Yuan* “Nonaggregational Shape-Persistent Cyclo[6]aramide and Its Macrocyclic Effect toward Binding Secondary Ammonium Salts in Moderately Polar Media” Org. Lett., 2013, 15, 4670-4673.

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