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新浦京8883平台
师资力量

董顺喜     教 授、博导

研究方向:不对称合成,稀土有机配合物催化

联系方式:          Email:dongs@scu.edu.cn

个人主页:点击进入

简历:

教育经历

2004.092008.06 四川大学  化学专业  理学学士学位

2008.092013.06 四川大学  有机化学  理学博士学位  导师:冯小明

研究及工作经历

2013.112016.02 德国亚琛工业大学,洪堡学者 (Carsten Bolm教授)

2016.072017.12 德国明斯特大学,博士后 (Gerhard Erker教授)

2018.012021.08 四川大学,化学学院,特聘研究员

2021.09~至今 四川大学,化学学院,教授

通讯地址:四川省成都市九眼桥望江路29号新浦京8883平台

主要研究方向

新型手性配体和催化剂的设计合成

稀土金属有机配合物催化

生物活性分子的高效合成

主要工作业绩

研究经历

董顺喜博士毕业于四川大学,师从冯小明教授,博士研究方向主要是手性胍类小分子催化剂的设计、合成及其在吖内酯参与的环化反应中的应用。2013作为洪堡学者赴德国亚琛工业大学Carsten Bolm教授课题组开展博士后研究工作,主要从事氨基酸衍生的pentathiepin设计合成以及手性氮杂环卡宾(NHC)催化不对称转化领域研究。2016年,加入德国明斯特大学Gerhard Erker课题组,开展新型受阻Lewis酸碱对(FLP)的设计合成及其反应性研究。2018年加入新浦京8883平台,主要从事(1)手性双氮氧金属配合物催化;(2)新型手性稀土金属有机配合物催化剂设计合成及其在不对称C-H官能化、氢元素化等反应中的应用研究。截至目前,已取得一系列创新性的研究成果,Acc. Chem. Res., Chem. Soc. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., CCS Chem., ACS Catal., Sci. China Chem., Org. Lett., Chem. Commun.等刊物发表SCI论文40余篇,多篇工作被Synfacts杂志专题亮点评述。

主要奖励和荣誉

2013年 获德国洪堡学者博士后奖学金

2019年 四川省引进海内外高层次人才计划

2019年 四川大学双百人才工程” B计划

2019年 教育部高等学校科学研究优秀成果奖自然科学一等奖(排名第四)

2020年 四川大学青年科技学术带头人培育项目资助

2020年 四川大学 大学生创新创业教育优秀指导教师

2020年 四川大学 基于智慧教学环境探究式小班化教学质量优秀奖

2020 年 四川大学学术新人奖

2021Thieme Chemistry Journals Award

2021年 第十三批四川省学术与技术带头人后备人选

2023年参与主讲的《手性技术》被认定为四川省首批高等学校课程思政典型案例(第四主讲人)

2024The Distinguished Lectureship Award of The CSJ Asian International Symposium

学术任职

2022年~2025Chinese Chemical Letters 第四届青年编委会委员

代表性成果(获奖成果、专著、论文、专利)

代表性论文:

1. Dong, S. X.; Feng, X. M.; Liu, X. H.* Chiral Guanidine and Their Derivatives in Asymmetric Synthesis, Chem. Soc. Rev. 2018, 47, 8525.

2. Dong, S. X.; Liu, X. H.*; Feng, X. M.* Asymmetric Catalytic Rearrangements with a-Diazocarbonyl Compounds, Acc. Chem. Res. 2022, 55, 415. (封面论文).

3. Tang, Q.; Fu, K.; Ruan, P. R.; Dong, S. X.*; Su, Z. S; Liu, X. H.; Feng, X. M.* Asymmetric Catalytic Formal 1,4-Allylation of β,γ-Unsaturated α-Ketoesters via Allylboration/Oxy-Cope Rearrangement, Angew. Chem. Int. Ed. 2019, 58, 11846.

4. Chen, Y. S.; Liu, Y.; Li, Z. J.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Tandem Insertion/[1,3]-Rearrangement: Highly Enantioselective Construction of a-Aminoketones, Angew. Chem. Int. Ed. 2020, 59, 8052.

5. Lin, Q. C.; Zheng, S. J.; Chen, L.; Wu, J.; Li, Z. J.; Liu, P. Z.; Dong, S. X.*; Liu, X. H.; Peng, Q.*; Feng, X. M.* Catalytic Regio- and Enantioselective Protonation for the Synthesis of Chiral Allenes: Synergistic Effect of the Counterion and Water. Angew. Chem. Int. Ed. 2022, 61, e202203650 (封面论文).

6. Tan, Z.; Chen, L.; Li, L. Y.; Li, Y. Z.; Luo, Y.; Wang, F.; Dong, S. X.*; Feng, X M.* Asymmetric Synthesis of α-Methylene-γ-butyrolactones via Tandem Allylboration/Lactonization: a Kinetic Resolution Process. Angew. Chem. Int. Ed. 2023, 62, e202306146.

7. Dong, S. X.; Cao, W. D.; Pu, M. P.; Liu, X. H.*; Feng, X. M.* Ligand Acceleration in Chiral Lewis Acid Catalysis. CCS Chem. 2023, 5, 2717–2735.

8. Zhu, C. H.#; Zhou, Y. Q.#; Zhang, J.; Li, J. F.; Zhang, Y. X.; Wang, F.; Feng, X. M.*; Dong, S. X.* Rare-Earth Metal Catalyzed Asymmetric Addition/Hydroamidination of Nitriles and Allylamines for the Concise Synthesis of Chiral Imidazolines, CCS Chem. 2024, accepted. DOI: 10.31635/ccschem.024.202403937.

9. Zeng, Z.#; Yang, L. Q. #; Xiao, Z. J.; Chen, L.; Zhong, Z. W.; Wang, F.; Liu, X. H.; Dong, S. X.*; Feng, X. M.* A Remarkable Influence of La(III)/N,N'‑Dioxide Structure on Asymmetric Formal Substitution of 3‑Bromo-3-substituted Oxindoles with TMSCN. ACS Catal. 2024, 14, 2908.

10. Mo, Y. H.; Ning, L. C.; Luo, Z.; Yang, L. K.; Tang, S.; Dong, S. X.* Zhou, Q. L.; Feng, X. M.* Asymmetric Photoenolization/Diels-Alder Reaction of 2-Methylbenzaldehydes and 2-Alkylbenzophenones with Chromones, ACS Catal. 2024, 14, accepted.

11. Li, D. W.; Ning, L. C.; Luo, Q. L.; Wang, S. Y.; Feng, X. M.; Dong, S. X.*. C-H alkylation of pyridines with olefins catalyzed by imidazolin-2-iminato-ligated rare-earth alkyl complexes. Sci. China. Chem. 2023, 66, 1804.

12. Wang, S. J.; Zhang, C.; F.; Li, D.; Zhou, Y. Q.; Su, Z. S.; Feng, X. M.; Dong, S. X.* New Chiral N-Heterocyclic Olefin Bifunctional Organocatalysis in α-Functionalization of β-Ketoesters, Sci. China. Chem. 2023, 66, 147.

13. Wang. S. Y.; Zhu, C. H.; Ning, L. C.; Li, D. W.; Feng, X. M; Dong, S. X.* Regioselective C-H alkylation of anisoles with olefins by cationic imidazolin-2-iminato scandium(III) alkyl complexes. Chem. Sci. 2023, 14. 3132 (cover picture).

14. Zhu, C. H.; Zhou, Y. Q.; Yang, J.; Feng, X. M.; Dong, S. X.* Lanthanide-catalyzed regio- and enantioselective hydrosilylation of aryl-substituted terminal and internal alkenes. Org. Chem. Front. 2023, 10, 1263.

15. Wang, S. J.; Yang, J.; Zeng, H. H.; Zhou, Y. Q.; Wang, F.; Feng, X. M.; Dong, S. X.* Asymmetric Formal Coupling of β-Ketoesters with Quinones Promoted by a Chiral Bifunctional N-Heterocyclic Olefin. Org. Lett. 2023, 25, 7247.

16. Wang, Y.; Yihuo, A. Y.; Wang, L. F. Dong, S. X.*; Feng, X. M.* Catalytic Asymmetric Synthesis of Chiral Azo Compounds via Interrupted Japp–Klingemann Reaction with Aryldiazonium Salts, Sci. China Chem. 2022, 65, 546.

17. Dong, P.; Li, Z. J.; Liu, X. H.; Dong, S. X.*; Feng, X. M.* Asymmetric Synthesis of Polycyclic Spiroindolines via the Dy-catalyzed Cascade Reaction of 3-(2-Isocyanoethyl)indoles with Aziridines, Org. Chem. Front. 2022, 9, 4591.

18. Tang, X. X.; Su, Z. S.; Lin, Q. C.; Lin, L. L.; Dong, S. X.*; Feng, X. M.* Asymmetric Catalytic α-Selective Allylation of Ketones with Allyltrifluoroborates using Dual-functional Chiral InIII/N,N′-dioxide Complex, Chin. J. Chem. 2022, 40, 1793.

19. Zhong, X.; Tan, J. Q.; Qiao, J. L.; Zhou, Y. Q.; Lv, C. D.; Su, Z. S.; Dong, S. X.*; Feng, X. M.* Catalytic Asymmetric Synthesis of Spirocyclobutyl Oxindoles and Beyond via [2+2] Cycloaddition and Sequential Transformations, Chem. Sci. 2021, 12, 9991.

20. Xu, C. R.; Qiao, J. L.; Dong, S. X.*; Zhou, Y. Q.; Liu, X. H.; Feng, X. M.* Asymmetric Synthesis of Dihydro-1,3-Dioxepines by Rh(II)/Sm(III) Relay Catalytic Three-Component Tandem [4+3]-Cycloaddition, Chem. Sci. 2021, 12, 5458. This article is part of the themed collection: 2021 Chemical Science HOT Article Collection. Highlighted by Synfacts 2021, 17, 0518.

21. Xiao, W. L.; Mo, Y. H.; Guo, J.; Su, Z. S.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Catalytic Enantioselective Synthesis of Macrodiolides and their Application in Chiral Recognition, Chem. Sci., 2021, 12, 2940.

22. Xiong, Q.; Luo, Q. L.; Zhang, T. H.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Catalytic Asymmetric Multicomponent Reaction of Isocyanide, Isothiocyanate and Alkylidene Malonates, Chem. Commun. 2021, 57, 7288.

23. Tang, X. X.; Su, Z. S., Yan, L. Q.; Tang, Q.; Dong, S. X.*; Lin, L. L. Xiaoming Feng, X. M.* Diastereo- and Enantioselective Synthesis of 3-Allyl-3-hydroxyoxindoles via Allylation of Isatins, Org. Lett. 2021, 23, 8419.

24. Dong, P.; Chen, L.; Yang, Z. D.; Dong, S. X.*; Feng, X. M.* Asymmetric Cycloisomerization/[3+2] Cycloaddition for Synthesis of Chiral Spiroisobenzofuran-1,3'-pyrrolidine Derivatives, Org. Chem. Front. 2021, 8, 6874.

25. Wang, F.; Feng, L. L.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Chiral N,N′-Dioxide-Iron(III)-Catalyzed Asymmetric Sulfoxidation with Hydrogen Peroxide, Chem. Commun. 2020, 56, 3233.

26. Li, D. W.; Wang, S. J.; Ge, S. L.; Dong, S. X.*; Feng, X. M. Asymmetric Synthesis of Axially Chiral Anilides via Organocatalytic Atroposelective N-Acylation, Org. Lett. 2020, 22, 5331.

27. Dong, S. X.; Daniliuc, C. G.; Kehr, G.; Erker, G.* Formation of Active Cyclic Five-membered Frustrated Phosphane/Borane Lewis Pairs and their Cycloaddition Reactions, Chem. Eur. J. 2020, 26, 745.

28. Luo, Y.; Zhang, H.; Wang, S. Y.; Zhou, Y. Q.; Dong, S. X.*; Feng, X. M.* Asymmetric Catalytic Diverse Ring Opening/Cycloadditions of Cyclobutenones with (E)-Alkenyloxindoles and (E)-Dioxopyrrolidines, Org. Lett. 2020, 22, 2645.

29. Ge, S. L.; Zhang, Y. Y.; Tan, Z.; Li, D. W.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Bimetallic Catalytic Tandem Reaction of Acyclic Enynones: Enantioselective Access to Tetrahydrobenzofuran Derivatives, Org. Lett. 2020, 22, 3551. Highlighted by Synfacts, 2020, 16, 0820.

30. Xiong, Q. Li, G. L.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Enantioselective Synthesis of Hydrothiazole Derivatives via an Isocyanide-Based Multicomponent Reaction, Org. Lett. 2019, 21, 8771.

31. Liu, W.; Zhou, P. F.; Lang, J. W.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, A Nickel(II)-Catalyzed Asymmetric Intramolecular Alder-ene Reaction of 1,7-Dienes, Chem. Commun. 2019, 55, 4479.

32. Li, X. Q.; Xiong, Q.; Guan, M. M.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Divergent Synthesis of Enantioenriched β-Functional Amines via Desymmetrization of meso-Aziridines with Isocyanides, Org. Lett. 2019, 21, 6096.

33. Zhong, X.; Tang, Q., Zhou, P. F.; Zhong, Z. W. Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Asymmetric Synthesis of Polysubstituted Methylenecyclobutanes via Catalytic [2+2] Cycloaddition Reaction of N-Allenamides, Chem. Commun. 2018, 54, 10511. Highlighted by Synfacts 2018, 14, 1154.

书籍章节:

1. Dong, S. X.; Zhao, J. N.; Feng, X. M.* Comprehensive Chirality, Second Edition, Volume 6, Chapter 1. Introduction and Remarks, Elsevier, 2023.

2. Zhao, J. N.; Dong, S. X.; Feng, X. M.* Comprehensive Chirality, Second Edition, Volume 6, Chapter 9. [4+2]-Cycloadditions (Inverse-Electron-Demand Hetero-Diels–Alder Reaction), Elsevier, 2023.

Before SCU:

34. Dong, S. X.; Frings, M.; Cheng, H. C.; Wen, J.; Zhang, D.; Rabbe, G.; Bolm, C.* Organocatalytic Kinetic Resolution of Sulfoximines. J. Am. Chem. Soc. 2016, 138, 2166. Highlight by Synfacts 2016, 12, 634.

35. Dong, S. X.; Liu X. H.*; Zhu, Y.; He, P.; Lin, L. L.; Feng, X. M.* Organocatalytic Oxyamination of Azlactones: Kinetic Resolution of Oxaziridines and Asymmetric Synthesis of Oxazolin-4-ones. J. Am. Chem. Soc. 2013, 135, 10026. Highlight by Synfacts (2013, 1006).

36. Dong, S. X.; Liu, X. H.; Chen, X. H.; Mei, F.; Gao, B.; Lin, L. L.; Feng, X. M.* Chiral Bisguanidine-Catalyzed Inverse-Electron-Demand Hetero-Diels-Alder Reaction of Chalcones with Azlactones. J. Am. Chem. Soc. 2010, 132, 10650. Highlight by Synfacts (2010, 1105).

37. Dong, S. X.; Frings, M.; Zhang, D.; Guo. Q. Q.; Danilliuc, C. G.; Cheng, H. C.; Bolm, C.* Organocatalytic Asymmetric Synthesis of trans-γ-Lactams. Chem. Eur. J. 2017, 23, 13888.

38. Dong, S. X.; Wang, L.; Wang, T.; Daniliuc, C. G.; Brinkkötter, M.; Eckert, H.; Kehra. G.; Erker, G. Formation and Reactions of Active Five-membered Phosphane/borane Frustrated Lewis Pair Ring Systems. Dalton Trans. 2018, 47, 4449.

39. Dong, S. X.; Liu, X. H*.; Zhang, Y. L.; Lin, L. L.; Feng, X. M *. Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt. Org. Lett. 2011, 13, 5060.

40. Liu, X. H.; Dong, S. X.; Lin, L. L.; Feng, X. M.* Chiral Amino Acids-Derived Catalysts and Ligands. Chin. J. Chem, 2018, 36, 791.

41. Guo, J.; Dong, S. X.; Zhang, Y. L.; Kuang, Y. L.; Feng, X. M.* Chiral Scandium(III)-Catalyzed Enantioselective α-Arylation of N-Unprotected 3-Substituted Oxindoles with Diaryliodonium Salts. Angew. Chem., Int. Ed. 2013, 52, 10245. Highlight by Synfacts (2013, 1262).

42. Wang, L.; Dong, S. X.; Daniliuc, C. G.; Liu, L.; Grimme, S.; Knitsch, R.; Eckert, H.; Hansen, M. R.; Kehra. G.; Erker, G. Formation of Macrocyclic Ring Systems by Carbonylation of Trifunctional P/B/B Frustrated Lewis Pairs. Chem. Sci. 2018, 9, 1544.

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